NCT05418231尚未招募不适用
Observation of the Natural Course of Dry Age-related Macular Degeneration
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2022年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Visual acuity
研究概览
简要总结
This research will study natural course of dry AMD in Chinese population, screen fundus imaging indicators for patients with Chinese dry AMD, describe the clinical features of Chinese patients with dry AMD, and obtain a biological sample library of dry AMD mainly in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •50-85 yrs male or female AMD patients
- •Dry-AMD patients in either early, intermediate, or intermediate-to-late stage confirmed by fundus examinations.
排除标准
- •Any eye with disease that would interfere with the retinal examinations
- •Research eye with CNV or high myopia
- •Surgeries that may interfere with AMD evaluation
- •Long-term uses of medications that are associated with retinal or neural toxicities.
- •IOP more than 26 mmHg
- •Received cataract surgery in 3 months.
- •Other conditions: diseases that causes less than 5 years survival; any condition that causes high risk of drop-out, or low compliance, for instance cognition disorder; have been involved in other trial that interfere with the current visit plan; taking other angiogenesis Inhibitors drugs for treating cancer.
- •Other conditions not suitable for the current study
结局指标
主要结局
Visual acuity
时间窗: 60 months
A typical ETDRS chart that if frequently used for visual acuity testing
次要结局
- The rate of 5-year progression(60 months)
- Drusen density and shape(60 months)
- GA growth rate(60 months)
研究者
Xiaodong Sun
Professor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
研究点 (1)
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