Autologous platelet rich plasma (A-PRP) combined with pelvic floor muscle training for the treatment of female stress urinary incontinence (SUI): A randomized control clinical trial
- Conditions
- Stress Urinary Incontinence , Famle SUIStress Urinary Incontinence , Platelet rich plasma
- Registration Number
- TCTR20230605003
- Brief Summary
The 1h PWT decreased significantly in the APRP with PFMT group but only slightly in the PFMT group at the 5 month follow up. There was a statistically significant between group difference in the 1 h pad weight of about 8 g in favor of the A PRP with PFMT group. A statistically significant difference in symptoms of SUI measured by the questionnaires was found between the APRP + PFMT group and the PFMT group at the 2 and 5month follow up assessments.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Diagnosed SUI by ICIQ UI SF score of 1 to 12 plus 1 hr Pad test more than 1 gram Mild to moderate SUI From ICIQ UI SF score Cough test positive Never received APRP treatment Did not use any SUI treatment procedure within 3 months Never undergone antiincontinence procedures Willing to follow the research protocol follow up Informed consent
OAB
Pelvic organs prolapse of anterior compartment
Thrombocytopenia Anemia
Coagulopathy Pregnancy Urinary retention obesity body mass index more than 35 Urinary tract infection Undiagnosed abnormal vaginal bleeding Taking corticosteroid or immunosuppressants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 hour pad weight test at 1st and 3rd month 1 hour pad weight test
- Secondary Outcome Measures
Name Time Method IQOL score at 1st and 3rd month IQOL score,ICIQ-FLUT score at 1st and 3rd month ICIQ-FLUT score,PGI score at 1st and 3rd month PGI score,Adverse events at 1st and 3rd month Adverse events