Verapamil effect on COPD
Phase 1
- Conditions
- Chronic obstructive pulmonary disease.Diseases of the respiratory systemJ00-J99
- Registration Number
- IRCT20170210032478N1
- Lead Sponsor
- ational Research Institute of Tuberculosis and Lung Diseases
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
All ICU- admitted COPD patients
Exclusion Criteria
pregnancy
sever hepato renal dysfunction
AV block or arrythmia
EF less than 40%
verapamil hypersensitivity
beta-adrenergic receptor drugs
QT disorders in patients
Bradycardia
co- administration of Digoxin
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial Oxygenation Blood gaz. Timepoint: 20 minutes after taking the medication or placebo for 3 days, Q 12 h. Method of measurement: Arterial Blood Gaz.;BORG scale. Timepoint: 20 minutes after taking the medication or placebo for 3 days, Q 12 h. Method of measurement: Tacking History.
- Secondary Outcome Measures
Name Time Method