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Radiotherapy to lungs for COVID-19 pneumonia

Phase 2
Conditions
Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2021/05/033868
Lead Sponsor
Kolhapur Cancer Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients with RT-PCR proven COVID-19 infection with moderate to severe pneumonia with National Early Warning Score [NEWS] 5 or more.

Exclusion Criteria

1.Patients requiring mechanical ventilation

2.Prior lobectomy or pneumonectomy

3.Prior thoracic radiotherapy

4.Prior chemotherapy or other systemic therapy with potential for pulmonary toxicity

5.Prior radio-sensatization

6.Severe pre-existing heart disease e.g. New York Heart Association [NYHA] functional class 3 or higher, congestive cardiac failure

7.History of Bone marrow or solid organ transplant

8.Known history of autoimmune collagen vascular disease

9.Known hereditory syndrome with increased sensitivity to ionizing radiation e.g. ataxia-telengiectasia or Fanconi anemia

10.Pregnancy

11.Inability to lie down supine and flat for radiotherapy

12.Inability to provide informed consent or lack of authorized representative who can provide informed consent.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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