Probiotics trial
Phase 2
Completed
- Conditions
- Aspirin-induced small bowel injuries
- Registration Number
- JPRN-jRCTs031200395
- Lead Sponsor
- Suzuki Takayoshi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1) Older than 20 y.o.
2) Patients who plan to have a colonoscopy
3) Patients who gave written informed consent before entry in this study
Exclusion Criteria
1) Patients who received antibiotics within 6 months before registration
2) Patients who regularly use other lactic acid bacteria preparations
3) Patients allergic to dairy products
4) A person who is determined to be inappropriate by the research director or co-workers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intestinal bacterial profile in the stool
- Secondary Outcome Measures
Name Time Method 1)Tight junction damage<br>2)COX expression<br>3)Amounts of mucosal prostaglandins<br>4)Existence ratio of immune cells<br>5)Intestinal bacterial profile (wash, biopsy tissue)<br>6)Amounts of calprotectin in the stool