Stapled or endloop closure of the appendiceal stump in laparoscopic appendectomy. A multicenter blinded randomised trial

• Conditions: appendicitis; 10017969; 10017998

• Registration Number: NL-OMON34175
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 1200

Inclusion Criteria

Patient eligible for laparoscopy
Clinical suspicion for acute appendicitis
Appendicitis on ultrasound, CT or MRI

Exclusion Criteria

Perforation of the appendiceal base
Inflammation of the caecum

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome parameters are superficial and intra-abdominal infections.<br /><br>Superficial trocar wound infections demand opening of the wound and additional<br /><br>wound care. After discharge, patients will visit the outpatient department more<br /><br>frequently and return to daily activities is delayed until sepsis has resolved.<br /><br>Intra-abdominal abscesses will require percutaneous drainage or surgery<br /><br>resulting in prolonged hospital stay or readmission after discharge.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Postoperative quality of life at two, four and twelve weeks (SF-36, EQ-5D)<br /><br>operating time, conversion rate, overall morbidity, hospital stay, return to<br /><br>work or school, direct and indirect medical costs (direct: equipment, operating<br /><br>time, infectious complications and indirect: return to work, daily activity) .</p><br>