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Clinical Trials/NCT04328857
NCT04328857
Recruiting
N/A

Experimentation of Sensorized Pseudoelastic Orthoses Produced by Additive Manufacturing

IRCCS Eugenio Medea1 site in 1 country34 target enrollmentOctober 1, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acquired Brain Injury
Sponsor
IRCCS Eugenio Medea
Enrollment
34
Locations
1
Primary Endpoint
Joint Stiffness of affected upper limb joint
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

The proposed clinical investigation plan is a pivotal controlled study with two parallel groups, has a total duration of 12 months and involves the recruitment of 34 pediatric patients suffering from acquired brain injury.

The primary objective of the clinical study is to evaluate the improvement of joint stiffness through the use of sensorized pseudoelastic orthoses for the rehabilitation of pediatric patients with acquired brain injury.

The effectiveness of the treatment in terms of joint stiffness (primary outcome) will be assessed and the effect of the treatment will be quantified with clinical evaluation scales and instrumental measurements by means of an optoelectronic system and isokinetic machine. The tolerability and acceptability of the device will also be checked.

Registry
clinicaltrials.gov
Start Date
October 1, 2020
End Date
May 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
IRCCS Eugenio Medea
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Quadriplegia or acquired hemiplegia.
  • Age 6-20 years.
  • Dystonic, dyskinetic, spastic.
  • Chronic phase patients (\> 1 year post event).
  • Spastic syndrome with Ashworth Score (AS) for the limb of interest\>
  • Collaborative.

Exclusion Criteria

  • Fixed limitations of the joint.
  • Joint pain.
  • Skin allergies.
  • Behavioral and psychiatric disorders (eg, emotional problems, anxiety, panic attacks).

Outcomes

Primary Outcomes

Joint Stiffness of affected upper limb joint

Time Frame: After 4 weeks of treatment

Quantitative measure performed by means of an isokinetic machine (Unit of measure: Nm/°). Changes in joint stiffness following the use of new customized devices during a rehabilitation treatment period. Lower stiffness is better.

Secondary Outcomes

  • Melbourne Upper Limb Assessment 2(After 4 weeks of treatment)
  • Range of motion of target joint during a pointing-forward task(After 4 weeks of treatment)
  • Quality of Upper Extremity Skills Test(After 4 weeks of treatment)
  • Active range of motion(After 4 weeks of treatment)
  • Passive range of motion(After 4 weeks of treatment)
  • Modified Ashworth Scale(After 4 weeks of treatment)

Study Sites (1)

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