ACTRN12610000167066招募中未知
In very preterm infants who are being extubated to nasal continuous positive airway pressure (CPAP), does a continuous positive airway pressure (CPAP) recruitment maneuvre post extubation improve global and regional end-expiratory lung volume, thoracoabdominal asynchrony and work of breathing when compared to no recruitment maneuvre?
Professor Peter Davis0 个研究点目标入组 50 人开始时间: 2010年2月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 24 Weeks 至 32 Weeks（—）
- 性别
- All
入选标准
- •Ventilated infants less than 32 weeks gestational age who are being extubated to nasal CPAP who have an inspired fraction of oxygen (FiO2) requirement < 0.4 to maintain saturations 88-92%
排除标准
- •Infants will be excluded if they are at risk of being intubated secondary to increasing FiO2 requirements or have multiple episodes of apnoea requiring stimulation; are at risk of being intubated in the next 2-3 hours post-extubation; are receiving NIPPV (non-invasive positive pressure ventilation; have a major congenital anomaly that might have an adverse effect on breathing or ventilation, apart from prematurity or asphyxia; are too unstable for routine nursing and have skin that is too fragile for conventional ECG electrode placement
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