JPRN-jRCT2080220921
Unknown
Phase 1
A Phase I, Open-label, Multiple-dose, Dose-escalation Study To Assess the Safety and Tolerability of AZD8931 Monotherapy in Japanese Patients With Advanced Solid Malignancies and in Combination With Paclitaxel in Japanese Female Patients With Advanced Breast Cancer
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- AstraZeneca
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Cancer that is refractory to standard therapies, or for which no standard therapies exist (monotherapy part)
- •\-Patients suitable for Paclitaxel chemotherapy, who are not candidates for hormonal and anthracycline therapy (combination part)
- •\-Life expectancy more than 12 weeks
Exclusion Criteria
- •\-Inadequate kidney, liver, heart, gastric, lung or eye function
- •\-Brain metastases
- •\-Hypersensitive to paclitaxel (combination part)
Outcomes
Primary Outcomes
Not specified
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