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The effect of metformin on reducing preeclampsia

Phase 3
Recruiting
Conditions
Pre-eclampsia.
Pre-eclampsia
Registration Number
IRCT20191104045328N14
Lead Sponsor
Arak University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
80
Inclusion Criteria

Pregnant mothers with low pregnancy-related plasma protein A referred to kousar Clinic
Normal arterial Doppler ultrasound
Age 18-50 years
Consent to participate in the study

Exclusion Criteria

History of intrauterine growth restriction or preeclampsia, gestational hypertension or pregnancy complications in previous pregnancies
History of congenital disease
History of liver or kidney failure

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Functional liver enzymes. Timepoint: in the 14th, 28th, 32nd weeks of pregnancy and at the time of delivery. Method of measurement: laboratory test.;Systolic and diastolic blood pressure. Timepoint: in the 14th, 28th, 32nd weeks of pregnancy and at the time of delivery. Method of measurement: Mercury sphygmomanometer.;Proteinuria. Timepoint: in the 14th, 28th, 32nd weeks of pregnancy and at the time of delivery. Method of measurement: Urinalysis test.;Preterm delivery. Timepoint: Delivery between 20 and 37 weeks. Method of measurement: Delivery.;Low birth weight. Timepoint: Birth weight less than 2500 grams. Method of measurement: scales.;Type of delivery. Timepoint: How the baby is born. Method of measurement: Cesarean-vaginal.
Secondary Outcome Measures
NameTimeMethod
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