Effects of non-surgical periodontal therapy on periodontal laboratory and clinical data as well as on disease activity in patients with rheumathoid arthritis

niversity of Medicine and Pharmacy Cluj-Napoca0 sites36 target enrollmentNovember 24, 2016

Overview

No summary available.

Registry

who.int

Start Date

November 24, 2016

End Date

TBD

Last Updated

9 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Medicine and Pharmacy Cluj-Napoca

•1\. Moderate or severe chronic periodontitis; \>30 years of age
•2\. \=10 natural teeth present in the oral cavity
•3\. Full\-mouth plaque scores (FMPS) \=30% after oral hygiene instructions
•4\. No other systemic diseases or medications except for RA, which are known to influence periodontal conditions/treatment outcome (e.g. Down Syndrome, HIV, Diabetes Mellitus type 1 and 2\)
•5\. DAS28\=3\.2
•6\. No infectious or heart diseases that need prophylactic administration of antibiotics before dental treatment
•7\. No liver disease; no head and neck radiation therapy

•1\. Non\-surgical periodontal therapy within the previous 12 months
•2\. Systemic or local use of antibiotics within the previous 3 months
•3\. Medication with a possible influence on the periodontium (e.g., ciclosporines, phenytoines, calcium channel blockers)
•4\. Pregnancy or lactation
•In the RA group, RA was diagnosed according to the criteria set by the American College of Rheumatology;