Renal Outcomes in the early use of vasopressin in the treatment of septic shock - EVSS

Azienda Unita Sanitaria Locale Di Bologna0 个研究点目标入组 242 人开始时间: 2023年11月14日最近更新: 2024年7月22日

适应症

试验速览

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•Patients suffering from septic shock hospitalized in an intensive setting within 24 hours of clinical diagnosis, Capable of expressing informed consent to treatment, Aged over 18 years and under 80 years of age, Male and female, Norepinephrine dosage equal to or greater than 0.25 mcg/kg/min according to the patient's ideal weight (IBW)

•Patients in the absence of consent to participate in the study and to the processing of personal and particular data, Single kidney patients, Patients with bilateral renal hypoplasia, Patients undergoing kidney transplant, Patients undergoing haemoperfusion with an adsorbent cartridge for bacterial endotoxin, Patients under 18 years of age or over 80 years of age, Patients who died within the first 24 hours of admission to the ICU, Patients requiring a norepinephrine dosage lower than 0.25 mcg/kg/min in the first 24 hours of hospitalization in the ICU, Patients with recent acute coronary syndrome (within the previous 7 days), Patients with allergy/intolerance to the drugs used in the study, Pregnant patients, Patients who need to start renal replacement treatment within 24 hours of admission to the ICU for dialysis emergencies that cannot be deferred, Patients with a history of end-stage renal failure or already undergoing dialysis treatment (CKD stages 4 and 5, with glomerular filtration < 30 ml/min)

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