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Medication Dispenser to Improve Care at Home for the Elderly

Not Applicable
Withdrawn
Conditions
Medication Adherence
Cognitive Impairment
Interventions
Other: SME only
Device: SME + Karie Device
Registration Number
NCT03511027
Lead Sponsor
Lee Verweel
Brief Summary

The purpose of this study is to investigate the efficacy of the Karie Automated Medication delivery device in enhancing medication adherence among a group of elderly patients with mild to moderate cognitive decline.

Detailed Description

Given the risks associated with poor adherence and the apparent contribution of good adherence to reducing hospitalizations and emergency department (ED) visits, interventions for promoting good adherence should be pursued. To this end, a number of devices have been developed to promote medication adherence, though with limited success due to reliability, cost, etc. The purpose of this study is to investigate the efficacy of the Karie Automated Medication Delivery Device in enhancing medication adherence among a group of community-dwelling patients immediately following discharge from inpatient rehabilitation.

This study will utilize a multi-site randomized controlled trial design. One week prior to discharge from inpatient rehab, consenting patients will be randomly assigned to receive medication self-management education only (SME) or medication self-management education + Karie (SME+K). Both sites (West Park Healthcare Centre, and CapitalCare) will recruit 150 participants for the study. At each site, 75 patients will be in the intervention group (SME + Karie) and 75 will be in the control group (SME only).

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Need to manage medications independently at home
  • Stabilized on medication, as per pharmacist/physician discretion; and
  • Mild-moderate cognitive/physical impairments, as per OT assessment
  • Montreal Cognitive Assessment (MoCA) score not less than 16
  • English speaking
Exclusion Criteria
  • Absent from community for more than one month during study
  • Inability to access study site pharmacy following discharge

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control (SME only)SME onlyWest Park has a "Self-Medication Education Program" policy in place which seeks to establish independent medication self-medication capacity during the inpatient stay. Eligibility criteria for SME include a need to manage medications independently at home; stabilized on medication (as per pharmacist/physician discretion); and mild-moderate cognitive/physical impairments (as per an OT assessment). During SME participants receive training by an Occupational Therapist, followed by a 5-day self-medication performance assessment by an Registered Nurse prior to discharge. Participants in the SME group will fill prescriptions as usual for the duration of study.
Intervention (SME + Karie Device)SME + Karie DevicePatients randomly assigned to receive SME+Karie will 1) undergo Screening for Self Medication Readiness to determine self-management capacity, 2) will receive self-medication education (SME) by a study Occupational Therapist, and 3) receive a 5-day self-medication performance assessment by an Registered Nurse prior to discharge. In addition, this group will receive orientation to the Karie Automated Medication Delivery by the study Occupational Therapist. The participants in the intervention arm will use the Karie device for all applicable medications for the study duration.
Primary Outcome Measures
NameTimeMethod
Change in Medication AdherenceBaseline (Time 0 Months), 3-months post-baseline(Time 3 Months), 6 months post-baseline (Time 6 Months)

The Medication Adherence Questionnaire (MAQ) and medication 7 day recall will measure participants adherence to their medications over time.Both of these measures will be taken at the same time-points throughout the study.

Secondary Outcome Measures
NameTimeMethod
Change in Quality of LifeBaseline (Time 0M), 3-months post-baseline(Time 3M), 6 months post-baseline (Time 6M)

The investigators will use the EQ-5D to measure changes in quality of life throughout the study.

Beliefs about medicationBaseline (Time 0M)

The Beliefs About Medication questionnaire, assesses participants cognitive representations of medication.

Change in Self-Medication BehavioursBaseline (Time 0M), 3-months post-baseline(Time 3M), 6 months post-baseline (Time 6M)

The investigators will use the Self-Efficacy for Appropriate Medication Scale (SEAMS) to determine participants behaviours and attitudes about self-medication

Economic Analysis3 months post-baseline (Time 3M), 6 months post-baseline (Time 6M)

To determine the affect that the Karie device has on economic indicators, the investigators will be observing staffing hours (OT, Pharmacist), medication costs, and medication wastage. This will be documented by staff and will be self-reported.

Change in Healthcare ConsumptionBaseline (Time 0M), 3-months post-baseline(Time 3M), 6 months post-baseline (Time 6M)

To determine any changes in healthcare consumption, the investigators will be observing the number of hospitalizations, visits to the GP, and visits to ER for all causes in all of the participants.

Sociodemographic FactorsBaseline (Time 0M)

The investigators will be collecting sociodemographic factors such as: Age, Gender, Education, Income, Postal Code.

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