Evaluation of Comfort With Xibrom (Bromfenac Ophthalmic Solution)0.09% and Nevanac (Nepafenac Ophthalmic Suspension) 0.1% Following Selective Laser Trabeculoplasty (SLT)
- Registration Number
- NCT00828477
- Lead Sponsor
- Bp Consulting, Inc
- Brief Summary
The objective of this study is to evaluate and compare the comfort of bromfenac or nepafenac following SLT.
- Detailed Description
Open label, single armed, cross over controlled study to evaluate comfort and IOP (Intraocular Pressure) changes of specific NSAIDs post SLT. Patients (n= 25, total 50 eyes) scheduled to undergo bilateral Selective Laser Trabeculoplasty (SLT) will instill bromfenac in the first eye to undergo SLT, and the contra lateral eye will receive nepafenac.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- > 18 years old, either gender or any race.
- Diagnosis of open-angle glaucoma or ocular hypertension requiring laser trabeculoplasty.
- Completion of written and informed consent/authorization prior to any study related procedures.
- Able to follow study protocol and likely to complete study schedule.
Exclusion Criteria
- Known sensitivity to NSAIDs.
- History of neovascular or ocular inflammatory disease.
- Current use of topical or systemic anti-inflammatory medications.
- Females of childbearing potential.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 1 Xibrom Xibrom (bromfenac) 2 Nevanac Nevanac (nepafenac)
- Primary Outcome Measures
Name Time Method Tolerability of study medication 28 days
- Secondary Outcome Measures
Name Time Method Intraocular pressure changes 28 days Visual Acuity 28 days
Trial Locations
- Locations (1)
Coburn-Kleinfeldt Eye Clinic
🇺🇸3340 6 mile Rd Livonia, Michigan, United States