JPRN-jRCTs021200008已完成2 期
Phase II study of galactosidase as therapy for type IV galactosemia
Kure Shigeo0 个研究点目标入组 3 人开始时间: 2020年6月8日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 3
研究概览
简要总结
This study demonstrated that the galactosidase treatment for type IV galactosemia can reduce blood galactose levels in lactose loading, suggesting the galactosidase may be a therapeutic agent for type IV galactosemia.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 1age old 至 < 10age old（—）
- 性别
- All
入选标准
- •Patients are diagnosed to type IV galactosemia by genetic test (pathogenic variants in GALM gene are identified by exome or direct sequencing) or GALM enzyme activity test.
排除标准
- •(1) Patients with severe liver disease or liver injury (AST, ALT > 1.25 x upper limits of normal)
- •(2) Patients have participated to other clinical study or trial
- •(3) Patients with constipation which is in need of treat
- •(4) Patients with psychological problem
研究者
相似试验
已完成
3 期
Glutamate for Metabolic Intervention in Coronary Surgery IICoronary Artery Bypass SurgeryPostoperative ComplicationsHeart FailureNCT02592824University Hospital, Linkoeping321
终止
2 期
High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in OsteosarcomaOsteosarcomaNCT00634322BTG International Inc.7
终止
1 期
Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed GlioblastomaGlioblastoma (GBM)NCT02046187St. Joseph's Hospital and Medical Center, Phoenix14
Unknown
2 期
Telaglenastat + Talazoparib In Prostate CancerProstate Cancer MetastaticNCT04824937Massachusetts General Hospital30
已完成
4 期
Galvus (Vildagliptin) vs Placebo in Combination With Metformin and InsulinType 2 DiabetesNCT01757587Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète39