German registry for thoracic aortic pathologies

Recruiting

Conditions: thoracic aortic pathologies
I71
Aortic aneurysm and dissection

Registration Number: DRKS00033646

Lead Sponsor: niversitätsklinikum Heidelberg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 5000

Inclusion Criteria

Patient's ability to consent, confirmed diagnosis of acute aortic pathology (PAU, IMH, type Stanford B aortic dissection, aortic aneurysm) of the thoracic aorta (without involvement of the aortic arch or ascending aorta). The origin of the aortic pathology must be in the area of the thoracic aorta, but can also spread to the abdominal aorta or iliac arteries.

Exclusion Criteria

Inadequate anonymization, lack of informed consent from study participants, patients are not able to give consent, traumatic aortic pathology due to accident, data transfer outside the Heidelberg Portal for Medical Data Models (https://medical-data-models.org)

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The main criterion is to examine whether genetic mutations in candidate genes or genetic risk variants can be identified in affected patients

Secondary Outcome Measures

Name	Time	Method
As secondary criteria, the clinical outcome for the therapy options (surgical therapy, endovascular therapy, conservative therapy) will be examined and evaluated.