To explore the application value of high frequency ultrasound in evaluating the effect of Simiao powder in the treatment of gouty arthritis based on the study of histopathology and multi-omics
- Conditions
- damp heat accumulation type gouty arthritis
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1) The disease diagnosis meets the 2015 ACR/EULAR gout classification criteria;
2) The first visit was in the acute stage of gout (the attack time was less than 7 days), with knee joint swelling and pain as the main joint symptom;
3) Ultrasound examination showed clear knee joint effusion, synovial membrane, double track sign or crystal deposition or tophi;
4) Meet the diagnostic criteria of TCM syndromes of damp-heat accumulation syndrome;
5) Age between 20-60 years old.
6) Voluntarily participate in the trial and sign the informed consent.
1) Patients with gout caused by certain drugs (such as proton pump inhibitors, low-dose aspirin, etc.), tumor radiotherapy and chemotherapy, etc. or secondary to diseases such as kidney disease, blood disease, and xanthine urethral deposition;
2) The first diagnosis is in the non-acute stage of gout;
3) Combined with other rheumatic diseases such as osteoarthritis and rheumatoid arthritis;
4) Those with other knee joint diseases: such as knee joint septic arthritis, knee joint traumatic arthritis, etc.;
5) Acute exacerbated or poorly controlled chronic diseases such as hypertension, coronary heart disease, liver and kidney insufficiency;
6) Mental illness, lack of self-control, unable to express accurately or unable to cooperate with treatment.
7) Those with abnormal coagulation function.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method