To explore the application value of high frequency ultrasound in evaluating the effect of Simiao powder in the treatment of gouty arthritis based on the study of histopathology and multi-omics

适应症

试验速览

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•1) The disease diagnosis meets the 2015 ACR/EULAR gout classification criteria;
•2) The first visit was in the acute stage of gout (the attack time was less than 7 days), with knee joint swelling and pain as the main joint symptom;
•3) Ultrasound examination showed clear knee joint effusion, synovial membrane, double track sign or crystal deposition or tophi;
•4) Meet the diagnostic criteria of TCM syndromes of damp-heat accumulation syndrome;
•5) Age between 20-60 years old.
•6) Voluntarily participate in the trial and sign the informed consent.

•1) Patients with gout caused by certain drugs (such as proton pump inhibitors, low-dose aspirin, etc.), tumor radiotherapy and chemotherapy, etc. or secondary to diseases such as kidney disease, blood disease, and xanthine urethral deposition;
•2) The first diagnosis is in the non-acute stage of gout;
•3) Combined with other rheumatic diseases such as osteoarthritis and rheumatoid arthritis;
•4) Those with other knee joint diseases: such as knee joint septic arthritis, knee joint traumatic arthritis, etc.;
•5) Acute exacerbated or poorly controlled chronic diseases such as hypertension, coronary heart disease, liver and kidney insufficiency;
•6) Mental illness, lack of self-control, unable to express accurately or unable to cooperate with treatment.
•7) Those with abnormal coagulation function.

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