The Rutgers University Study of the Genetics of Blood Cancers
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 10,000
- 试验地点
- 1
- 主要终点
- Genetic risk variants associated with blood cancer
研究概览
简要总结
The goal of this study is to enroll at least 10,000 participants nationally including affecteds and unaffecteds via online study portal, collect surveys online and a saliva sample through the mail, sequence DNA, and conduct genetic analyses to identify novel variants and further study known variants associated with leukemia, lymphoma, myeloma and other blood cancers.
详细描述
This is an online research study to learn more about how genes affect your risk of blood cancers. No office visit is required and in return, participants may receive information about their genetic ancestry for free. This study will increase our understanding of the genetic basis of blood cancers, which is a crucial step in drug development to improve current treatment options. We seek a diverse population because diversity among participants maximizes the usefulness of the data. Participants will use our online study portal to answer questions about their health and provide their DNA via a saliva sample using a pre-paid mailer. Participation takes approximately 20 minutes. Participants will be invited to share data from their electronic health records, but this is not required for study participation. We keep participants engaged with short monthly newsletters.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 110 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18 years or older
- •currently living in the United States
- •have access to the internet and a computer, laptop, tablet or smartphone
- •willing to provide written informed consent for participation
- •willing to provide DNA via a saliva sample using a collection kit mailed to your home
- •willing to complete a survey with questions about health related to the study of blood cancer.
排除标准
- •Not able to meet or fulfill any of the inclusion criteria
结局指标
主要结局
Genetic risk variants associated with blood cancer
时间窗: 2 years
Genetic factors will be measured through whole exome sequencing and genome-wide genotyping array, and then correlated with blood cancer subtype.
次要结局
未报告次要终点
研究者
Tara Matise, Ph.D.
Distinguished Professor
Rutgers, The State University of New Jersey