NCT00992303招募中不适用
Tissue Procurement and Outcome Collection for Radiotherapy Treated Patients and Healthy Participants
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 10,000
- 试验地点
- 2
- 主要终点
- Maintenance a Tissue Resource and Registry/Database
研究概览
简要总结
RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future.
PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy
详细描述
OBJECTIVES:
Primary
- To maintain and create a University of Texas Southwestern Medical Center (UTSW) Radiation Oncology Tissue Resource and Registry/Database that will be used to explore genetic variations contributing to clinical outcomes through tissue analysis and outcome correlation. Tissue will be stored by the UTSTR and the database managed by Radiation Oncology.
Secondary
- To document disease outcome (local recurrence, distant metastasis, overall survival) by treatment regimen and disease site.
- To document toxicity by treatment regimen and disease site.
- To establish a prospective registry/database consisting of patient demographics and outcomes to be used for future research.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •DISEASE CHARACTERISTICS:
- •Pathologically-proven diagnosis of malignancy
- •Planning treatment with radiation therapy
- •PATIENT CHARACTERISTICS:
- •Able to perform follow-up visits
- •Is a patient of the University of Texas Southwestern Medical Center physicians
- •PRIOR CONCURRENT THERAPY:
- •See Disease Characteristics
- •Participation in other clinical trials is allowed
- •Other prior or concurrent therapy for cancer, such as surgery and/or chemotherapy, is allowed.
- •Criteria for eligibility:
- •Able to provide written informed consent
- •Age greater than 18 years old
- •Males and Females are eligible
- •Any ethnicity is eligible
- •Criteria for ineligibility:
- •Patients not available for follow-up/future contact
排除标准
- 未提供
结局指标
主要结局
Maintenance a Tissue Resource and Registry/Database
时间窗: 10 years
Maintenance and creation of a University of Texas Southwestern Medical Center (UTSW) Radiation Oncology Tissue Resource and Registry/Database
次要结局
- Local recurrence(5 years)
- Distant metastasis(5 years)
- Toxicity by treatment regimen(1 year)
- Overall survival(5 years)
- Establishment of a prospective registry/database(10 years)
研究者
Robert Timmerman
Professor
University of Texas Southwestern Medical Center
研究点 (2)
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