Clinical and Radiographic Evaluation of Revascularization of Immature Anterior Permanent Teeth Using (CGF) Versus (BC)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 主要终点
- clinically successful treatment
研究概览
简要总结
The aim of this study is to compare clinical and radiographic evaluation treatment of necrotic immature permanent teeth using:
- Concentrated Growth Factor
- Blood Clot
详细描述
Rationale for conducting the research:
Concentrated growth factor (CGF) is relatively a new generation of platelet concentrate product, it contains more cytokines and growth factors compared with PRP and PRF also promotes the proliferation, migration, and differentiation of stem cells.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 8 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children aged between 8_14 years.
- •Anterior tooth diagnosed with necrotic pulp (due to trauma, caries, or anomaly) responded negatively to sensibility tests.
- •Teeth not indicated for post and core.
- •A cooperative and compliant patient/parent.
- •Patients not allergic to medicaments necessary to complete the procedure.
- •Patients with no history of chronic systemic diseases.
排除标准
- •Medically compromised patient.
- •Teeth with vertical fractures.
- •Non-restorable teeth.
- •Teeth when bleeding could not be induced.
- •Unable to attend follow-up visits.
结局指标
主要结局
clinically successful treatment
时间窗: 3,6,9,12 months
The treatment will be considered to be clinically successful when. Absence of pain will record it by verbal question to patient/ parent. Absence of tenderness to percussion) will record it by percussion test (by the back of the dental mirror) Absence of swelling and fistula or sinus tract -- will record it by visual clinical examination
次要结局
- Radiographic Success treatment(6, 12 months)
研究者
Hana Ahmed Omer
PhD researcher in pediatric dentistry and public health department
Cairo University