Effects of remote ischemic conditioning in critically ill patients on incidence and severity of acute kidney injury - pilot trial
Not Applicable
Recruiting
- Conditions
- N17OPS-2015: 8-98f (Complex intensive care treatments)Acute renal failure
- Registration Number
- DRKS00009030
- Lead Sponsor
- niversitätsklinikum Münster Klinik für Anästhesiologie, operative Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
critically ill patients on mechanical ventilator and analgosedation for at least 24 hours
- requirement of catecholamines (Epi/Norepi >= 0.1 µg/kg/min)
- unlimited intensive treatment for at least 2 days
- informed consent
Exclusion Criteria
- pregnancy
- History of unobserved circulatory arrest
- refusal of intensive care treatment or life-prolonging measures
- drug therapy with oral antidiabetics, sulfonamides, nicorandil
- Participation on another clinical intervention trial
- Persons with any kind of dependency to the investigator or employed by the sponsor or investigator
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method compliance with the study protocol
- Secondary Outcome Measures
Name Time Method - proportion of randomised patients<br>- frequency of patients with follow-up after 90 days<br>- Severity of acute kidney injury<br>- incidence of acute kidney injury<br>- requirement for renal replacement therapy<br>- mortality<br>- biomarker<br>