NL-OMON19978已完成不适用
Prospective study on the effects of rituximab on synovial tissue of patients with rheumatoid arthritis.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
研究概览
简要总结
/A
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Patients (18 years or older) with rheumatoid arthritis (ACR 1987 criteria) with active disease (at least 4/28 swollen and at least 4/28 painfull joints, and either ESR 28 mm or CRP 15 mg/l or morning stiffness 45 min);
- •2. Rheumatoid factor and/or anti-CCP positive;
- •3. Stable doses methotrexate (5-30 mg);
- •4. Stable doses prednisone (0-10 mg);
- •5. Previous anti-TNF treatment is allowed.
排除标准
- •1. Previous treatment with rituximab;
- •2. Intra-articular or parenteral corticosteroids within 4 weeks prior to inclusion.
研究者
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