Effects of letrozole in women with endometrioma undergoing ovarian stimulation for in vitro fertilizatio
Not Applicable
- Conditions
- Diseases of The genitoruinary system
- Registration Number
- KCT0003374
- Lead Sponsor
- Seoul National University Bundang Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
? Infertile woman participating in in vitro fertilization
? Patients with endometrioma
i) When ultrasonographic examination shows suspicious endometriotic cyst 3 cm or more
Exclusion Criteria
? Patients with poor ovarian response (based on Bologna criteria)
? Diagnosis of polycystic ovary syndrome (based on Rotterdam consensus)
? Patients with ovarian cysts other than endometrioma
? Patients with histoy of ovarian cystectomy or ovariectomy
? If the indication for IVF is a male factor (eg. total motile sperm count =10 million)
? Other medical conditions
? If other researchers judge that participation in clinical trials is inappropriate
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method number of retrieved oocytes
- Secondary Outcome Measures
Name Time Method rate of mature oocytes;fertilization rate;good quality(grade A or B) embryo formation rate;clinical pregnancy rate;abortion rate;ongoing pregnancy rate;cytokines (TNF-a, IL-6) of follicular fluid;survivin concentration of follicular fluid;reactive oxygen species (ROS) of follicular fluid