A Prospective Randomized Controlled Trial Comparing Transumbilical Single Incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer

Guoxin Li1 site in 1 country198 target enrollmentApril 2014

Overview

Compared with traditional open colectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its short- and long-term oncologic outcomes have been demonstrated.
In experienced surgeons' hands, single incision laparoscopic surgery is increasingly performed for colorectal disease, and even for malignant lesion because of its reduced incision-associated morbidity and scarring.
However, the safety and efficacy of single incision laparoscopic surgery for colorectal cancer has not yet been evaluated. Thus, the prospective randomized trial comparing single incision versus conventional laparoscopic surgery for colorectal cancer is needed.

Registry

clinicaltrials.gov

Start Date

April 2014

End Date

April 2022

Last Updated

12 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Sponsor

Guoxin Li

Responsible Party

Sponsor Investigator

Principal Investigator

Guoxin Li

M.D., Ph.D.

Nanfang Hospital, Southern Medical University

•18 years \< age \< 80 years
•Tumor located in rectosigmoid (defined as 10- to 30-cm from the anal verge)
•Pathological rectosigmoid carcinoma
•Preoperative T stage ranging from T1 to T4a according to the 7th Edition of AJCC Cancer Staging Manual
•Tumor size of 5 cm or less; 6) ECOG score is 0-1
•ASA socre is Ⅰ-Ⅲ
•Informed consent

•Body mass index (BMI) \>30 kg/m2
•Pregnant woman or lactating woman
•Severe mental disease
•Previous abdominal surgery
•Emergency operation due to complication (bleeding, perforation or obstruction) caused by colorectal cancer
•Requirement of simultaneous surgery for other disease