NCT04525482已完成不适用
Application of Early Goal-directed Sedation in Patients With Severe Brain Injury
Second Affiliated Hospital, School of Medicine, Zhejiang University0 个研究点目标入组 300 人开始时间: 2017年1月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 主要终点
- length of stay in ICU
研究概览
简要总结
EGDS management strategy was implemented in ICU patients with severe brain injury, the depth of sedation and GCS score were monitored, and the protective effects of EGDS strategy and standard sedation strategy on the brain of patients with severe brain injury were discussed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of severe craniocerebral injury
- •The GCS score is 6 to 12 points
- •Within 12 hours of intubation
- •The mechanical ventilation time is greater than 24 hours
- •Obtain written consent
排除标准
- •Pregnant women
- •Acute liver failure
- •Dementia or mental illness
研究组 & 干预措施
Control Group
No Intervention
No intervention was implemented
Intervention Group
Experimental
Early goal-directed sedation programs was implemented
干预措施: Early goal-directed sedation programs (Other)
结局指标
主要结局
length of stay in ICU
时间窗: through study completion, an average of 2 year
Mechanical ventilation time
时间窗: through study completion, an average of 2 year
Richmond Agitation-Sedation Scale
时间窗: through study completion, an average of 2 year
次要结局
- complication(through study completion, an average of 2 year)
研究者
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