NCT00231712Unknown不适用
Prospective Analysis of the Patterns of Immune Reconstitution Following Conventional or High-Dose Chemotherapy With Autologous/Allogeneic Stem Cell Transplant
Julius-Maximilians University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2005年3月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
The purpose of this study is to conduct an analysis of the influences of
- conventional chemotherapy
- high-dose chemotherapy followed by autologous stem cell transplant
- high-dose chemotherapy followed by allogeneic stem cell transplant on the recovery of the immune system.
Detailed analysis will help to better understand the pathways of recovery of the immune system following chemotherapy as well as the pathways of recovery of the immune system following autologous or allogeneic stem cell transplantation.
详细描述
Detailed analysis will be performed at preselected time points following therapy by
- standard flow cytometry in combination with intracellular cytokine/antigen staining
- spectratype analysis
- TREC assays
研究设计
- 研究类型
- Observational
- 观察模型
- Defined Population
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 —(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute leukemia treated according to current ALL-BFM 2002 protocol
- •Solid tumor treated according to current GPOH-protocol
- •Medulloblastoma treated according to HIT-2000 protocol
- •High-dose chemotherapy followed by autologous stem cell transplantation
- •High-dose chemotherapy followed by allogeneic stem cell transplantation
- •Written consent according to our institutional guidelines
排除标准
- •No written consent
研究者
研究点 (1)
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