Plaque Burden and Ischemia in MINOCA
Recruiting
- Conditions
- MINOCA
- Interventions
- Diagnostic Test: CT coronary angiography and [12N] NH3 PET-MR
- Registration Number
- NCT05681858
- Lead Sponsor
- University of Bergen
- Brief Summary
The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are:
* Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA
* Assess presence, extent and severity of myocardial ischemia in MINOCA
Participants will examined by CT coronary angiography and stress \[12N\] NH3 PET-MR.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Acute chest pain
- Elevated troponin
- Non-obstructive coronary arteries by coronary angiography
Exclusion Criteria
- Obstructive coronary artery disease
- Contraindications against CT coronary angiography or stress [12N] NH3 PET-MR
- Not able to give informed consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description CT coronary angiography and [12N] NH3 PET-MR CT coronary angiography and [12N] NH3 PET-MR All patients will undergo CT coronary angiography and stress \[12N\] NH3 PET-MR
- Primary Outcome Measures
Name Time Method Plaque burden 1 week Myocardial ischemia 1 week
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Clinical Science, University of Bergen
🇳🇴Bergen, Norway