NCT05681858
Recruiting
Not Applicable
Coronary Artery Plaque, Perivascular Inflammation and Myocardial Ischemia in Patients With Myocardial Infraction and Non-obstructive Coronary Arteries
ConditionsMINOCA
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- MINOCA
- Sponsor
- University of Bergen
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Plaque burden
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are:
- Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA
- Assess presence, extent and severity of myocardial ischemia in MINOCA
Participants will examined by CT coronary angiography and stress [12N] NH3 PET-MR.
Investigators
Mai Tone Lønnebakken
Professor M.D.
University of Bergen
Eligibility Criteria
Inclusion Criteria
- •Acute chest pain
- •Elevated troponin
- •Non-obstructive coronary arteries by coronary angiography
Exclusion Criteria
- •Obstructive coronary artery disease
- •Contraindications against CT coronary angiography or stress \[12N\] NH3 PET-MR
- •Not able to give informed consent
Outcomes
Primary Outcomes
Plaque burden
Time Frame: 1 week
Myocardial ischemia
Time Frame: 1 week
Study Sites (1)
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