Effectiveness of individualized homoeopathic medicine in treatment of rheumatoid arthritis - A Quasi experimental study
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- To evaluate the effectiveness of individualized homoeopathic medication in reducing the
研究概览
简要总结
This study aims to evaluate the effectiveness of individualized homoeopathic medicine in the treatment
of Rheumatoid Arthritis (RA). It is designed as a quasi-experimental, prospective clinical trial conducted
at the National Homoeopathy Research Institute in Mental Health, Kottayam. The primary objective is
to assess clinical improvement in RA symptoms using the Simplified Disease Activity Index (SDAI), while
the secondary objective is to examine changes in anti-CCP antibody levels, which are highly specific
biomarkers for RA.A total of 38 patients, selected via purposive sampling, will be enrolled based on
criteria including ACR score greater than or equal to 6 and anti-CCP greater than 20 IU/mL, ensuring the inclusion of patients with
definitive RA and a significant autoimmune component. Participants will receive individualized
homoeopathic treatment based on classical homoeopathic principles, with prescriptions determined
through repertorization using RADAR software and standard materia medica references. Clinical
assessments—including SDAI scoring and laboratory investigations will be carried out at baseline and
every three months during a 12-month intervention period, with a total study duration of 18 months.
Data will be statistically analyzed using SPSS, with significance set at p lessthan 0.05.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •20-70years both males and females ,Patients presenting with symmetrical polyarthritis , Anti-CCP antibodies greater than 20IU/mL.
排除标准
- •Patients with other severe systemic illness ,Pregnant women, lactating mothers, Immunocompromised patients.
结局指标
主要结局
To evaluate the effectiveness of individualized homoeopathic medication in reducing the
时间窗: Baseline,3rd month,6th month,9th month,12th month
disease activity in rheumatoid arthritis measured by simplified Disease Activity Index(SDAI).
时间窗: Baseline,3rd month,6th month,9th month,12th month
次要结局
- To assess the effectiveness of homoeopathic medicine in reducing the(levels of anti-CCP in rheumatoid arthritis.)
研究者
DrLVenkata Nagasai Charitha
National Homoeopathic Research Institute in Mental Health, kurichy, kottayam-