PRO*MDD: Effectiveness of outpatient treatment PROgrams for Major Depressive Disorder: Metacognitive Therapy vs. Behavioral Activatio

Not Applicable

• Conditions: F33; F32; Recurrent depressive disorder; Depressive episode

• Registration Number: DRKS00011536
• Lead Sponsor: Klinik für Psychiatrie und Psychotherapie, Universität zu Lübeck

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-13
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

Primary Diagnosis of MDD according to DSM-IV (SCID-I-Interview)
severity of depression > 16 Punkte in HRSD-Interview.
willingness to participate in the study (informed consent)
willingness to participate over a maximum of 6 months in the study and take part in the therapy session regularly (no plans to move or to have inpatient treatment)

Exclusion Criteria

lifetime diagnosis of psychotic disorder
lifetime diagnosis of bipolar disorder
IQ below 85
acute sucidality
acute serious substance abuse disorder, that calls for detoxication
Inadequate german language skills

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
primary outcome: severity of depressive symptoms assessed by the Hamilton Rating Scale for Depression (HRSD) at the end of treatment (6 months assessment)

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes address general psychopathology (BSI), quality of life (SF-12), psychosocial functioning and participation (WHODAS), course of other psychiatric disorders (SKID I und II), metacognitions, rumination and worying (MDD-S, MCQ-30, RSQ-D) as well as behavioral activation (BADS).Secondary Outcomes will be assessed at baseline as well as 3, 6, 12, 18 and 30months after start of treatment