Assessment of Work Productivity and Activities in Patients With Migraine Using the "WPAI (Work Productivity and Activity Impairment)" Questionnaire: Validity and Reliability Study of the Greek Version
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Greek Version of the Work Productivity and Activity Impairment Questionnaire for Migraine (WPAI:Migraine)
研究概览
简要总结
Migraine is a common neurological disorder that can substantially impair work productivity and daily functioning through both absenteeism and presenteeism. The Work Productivity and Activity Impairment Questionnaire for Migraine (WPAI:Migraine) is a brief patient-reported measure designed to assess migraine-related impairment in work and daily activities. Although the questionnaire has demonstrated validity and reliability in other populations, a validated Greek version is currently unavailable. This study aims to evaluate the validity and reliability of the Greek version of the WPAI:Migraine in individuals with episodic or chronic migraine, thereby providing an appropriate tool for assessing migraine-related work productivity and functional impairment in the Greek population.
详细描述
Migraine is one of the most common neurological disorders among working-age individuals worldwide and a major cause of lost work productivity. Migraine attacks not only cause pain and associated symptoms but also lead to work absenteeism, reduced productivity, and limitations in daily activities [1,2]. A study including 31 countries showed that 52% of individuals with at least 4 migraine days per month experienced an overall reduction in work performance due to migraine, and that this was attributable more to presenteeism than absenteeism [3]. The American Migraine Prevalence and Prevention Study reported that the cost of presenteeism was nearly three times that of absenteeism in patients with episodic migraine [4].
The Work Productivity and Activity Impairment Questionnaire (WPAI) is a brief and widely used patient-reported outcome measure that assesses the impact of chronic diseases on work performance. WPAI:Migraine, a migraine-specific version, has been found to be valid and reliable in American and Arabic populations of patients with episodic and chronic migraine [1,5]. International Headache Society (IHS) guidelines for preventive treatment trials in episodic and chronic migraine recommend the use of the WPAI [6,7]. Therefore, it is important to evaluate the impact of migraine not only through clinical parameters but also in terms of productivity and functioning [6,7].
In Greece, migraine studies have been conducted at the population level using pharmacological treatments and assessments. However, with regard to daily life and work productivity, there is currently no validated Greek WPAI:Migraine questionnaire available to assess migraine-related productivity loss. Availability of such a scale for the Greek migraine population is important for clinical applications, health-economics research, and evaluation of treatment outcomes [8,9].
Aim of the study - Hypotheses to be tested The aim of the present study is to investigate the validity and reliability of the Greek version of the WPAI:Migraine questionnaire in individuals with migraine and to determine whether it can be used as a valid and reliable tool for assessing work productivity and functioning in the Greek population.
Hypotheses:
研究设计
- 研究类型
- 观察性
- 观察模型
- 其他
- 时间视角
- 前瞻性
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- Diagnosis of migraine
- Age 18-70 years
- Ability to understand, read, write, and speak the Greek language
排除标准
- Presence of a headache disorder other than migraine
- History of systemic diseases (malignant, inflammatory, acute traumatic, infectious, surgical, neurological, psychiatric, or rheumatological conditions)
研究组 & 干预措施
Patients with Migraine
结局指标
主要结局
Greek Version of the Work Productivity and Activity Impairment Questionnaire for Migraine (WPAI:Migraine)
时间窗: Baseline and 7-14 days after baseline for test-retest reliability.
The validity and reliability of the Greek version of the WPAI:Migraine will be evaluated in patients with migraine. The questionnaire assesses work productivity and activity impairment over the previous 7 days, including absenteeism, presenteeism, overall work impairment, and activity impairment. Higher percentage scores indicate greater impairment.
次要结局
- Migraine-Related Disability(Baseline)
- Headache Impact(Baseline)
- Migraine-Specific Quality of Life(Baseline)
- Headache Pain Intensity(Baseline)
研究者
研究点 (1)
标识符
- NCT 编号
- NCT07847554
- 其他研究编号
- Approval Νο: 703, 3-6-2026
日期
- 首次提交
- (8天前)
- 首次发布
- (昨天)
- 主要完成日期
- (8个月后)
- 研究完成日期
- (9个月后)
- 最近核实
- (29天前)
- 最近更新
- (昨天)
监管与共享
- FDA 监管药物
- 否
- FDA 监管器械
- 否
- 个体参与者数据共享计划
- 否
- 是否有结果
- 否
Individual participant data (IPD) are not planned to be made publicly available. Data may be considered for sharing upon reasonable request and subject to applicable ethical and institutional requirements.