EUCTR2010-022472-31-GB进行中（未招募）不适用
The effect of Lidocaine and its Delivery in Patients with Chronic Cough - Lidocaine: Effect of Lidocaine in Chronic Cough
niversity Hospital of South Manchester0 个研究点目标入组 0 人开始时间: 2010年10月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Male and female subjects, age 18 years and over. - History of cough for more than 8 weeks. - Normal chest x ray. - Chronic idiopathic cough or chronic cough resistant to treatment of specific triggers.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
- •- Male and female subjects, age 18 years and over. - History of cough for more than 8 weeks. - Normal chest x ray. - Chronic idiopathic cough or chronic cough resistant to treatment of specific triggers.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •SMOKING STATUS: - Current smokers - Ex smokers with history of smoking > 20 pack years or those who have given up < 6 months ago. PROHIBITED MEDICATIONS: - Use of medications likely to suppress / affect cough including codeine, morphine, pregabalin, gabapentin, amitriptylline, angiotensin convertin enzyme inhibitors (type 1) and baclofen. - Use of any anti-arrhythmic medication. - Use of cimetidine, beta blockers, or diuretics. CARDIOVASCULAR CONDITIONS: - Sinoatrial disease, bradycardia or all types of heart blocks. - History of ischaemic heart disease or heart failure. - Clinically significant abnormal electrocardiogram (ECG) at Screening or Baseline. - History of cardiac surgery RESPIRATORY CONDITIONS: - Asthma. CENTRAL/PERIPHERAL NERVOUS SYSTEM CONDITIONS: - Epilepsy. - Myasthenia gravis. MISCELLANEOUS: - History of hepatic or renal dysfunction. - Porphyria - History of hypersensitivity to Lidocaine or related drugs. - Pregnancy or breast feeding. - Participation in another trial within the preceding 6 weeks. - Trauma or ulceration to oral mucosa. - History of chest or upper airway infection within the past 6 weeks. - Conditions which may affect cough response such as stroke, diabetes, Parkinson’s disease.
- •SMOKING STATUS: - Current smokers - Ex smokers with history of smoking > 20 pack years or those who have given up < 6 months ago. PROHIBITED MEDICATIONS: - Use of medications likely to suppress / affect cough including codeine, morphine, pregabalin, gabapentin, amitriptylline, angiotensin convertin enzyme inhibitors (type 1) and baclofen. - Use of any anti-arrhythmic medication. - Use of cimetidine, beta blockers, or diuretics. CARDIOVASCULAR CONDITIONS: - Sinoatrial disease, bradycardia or all types of heart blocks. - History of ischaemic heart disease or heart failure. - Clinically significant abnormal electrocardiogram (ECG) at Screening or Baseline. - History of cardiac surgery RESPIRATORY CONDITIONS: - Asthma. CENTRAL/PERIPHERAL NERVOUS SYSTEM CONDITIONS: - Epilepsy. - Myasthenia gravis. MISCELLANEOUS: - History of hepatic or renal dysfunction. - Porphyria - History of hypersensitivity to Lidocaine or related drugs. - Pregnancy or breast feeding. - Participation in another trial within the preceding 6 weeks. - Trauma or ulceration to oral mucosa. - History of chest or upper airway infection within the past 6 weeks. - Conditions which may affect cough response such as stroke, diabetes, Parkinson’s disease.
研究者
相似试验
已完成
3 期
Investigating the effect of Lidocaine injection into the airways in order to prevent lung infectioIRCT20201013049017N2Esfahan University of Medical Sciences60
已完成
2 期
The effect of of intravenus Lidocaine in comparision with oral Clonidine on heart rate and blood pressure after tracheal intubation in paitients undergo elective surgury with general anesthesiaPaitients undergo direct laryngoscopy and tracheal intubation with general anesthesia.Other complications of surgical and medical care, not elsewhere classifiedIRCT2014102819731N1Tehran University of Medical Science86
已完成
3 期
Effect of Lidocain and Epinephrin in EpisiotomyEpisiotomy repair.IRCT20200421047160N1Tehran University of Medical Sciences220
已完成
不适用
Influence of method to administer lidocaine into tracheapatient undergoing elective surgery under general anesthesiaJPRN-UMIN000006220ational Defense Medical College50
进行中（未招募）
1 期
The effect of lidocaïne (muscle relaxant) in two muscles of the upper leg in people who had a stroke and walk with a stiff knee because of the stroke.EUCTR2019-000403-32-NLRoessingh Research and Development18