Effect of Enoxaparin in treatment of neonate Thrombosis
Phase 1
Recruiting
- Conditions
- Dosage of enoxaparin in the treatment of neonatal thrombosis.
- Registration Number
- IRCT20220122053794N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Neonatal thrombosis
Thrombosis confirmed by color Doppler ultrasound or MRV spiral CT scan or angiography
Consensus of the treatment team to start anticoagulant treatment
Exclusion Criteria
Platelet count less than 50,000
Active bleeding
High risk of bleeding if anticoagulants are used
Creatinine higher than 1.5 times normal for age and sex
Liver failure that can interfere with the synthesis of coagulation factors and increase the risk of bleeding.
History of heparin sensitivity
Heparin-induced thrombocytopenic syndrome
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Elimination of thrombus determined by ultrasound. Timepoint: The first 30 days of life. In infancy. Method of measurement: Anti-Xa factor.By blood sampling method;Ultrasound to check for thrombosis.;Factor antiXa;. Timepoint: The first 30 days of life. Method of measurement: measurement by blood sampling.
- Secondary Outcome Measures
Name Time Method