Risk of Stroke in Pulmonary Embolism With a Patent Foramen Ovale (PFO)

Completed

• Conditions: Silent Stroke; Pulmonary Embolism; Patent Foramen Ovale

• Registration Number: NCT00831259
• Lead Sponsor: University Hospital, Caen

Brief Summary

Pulmonary embolism is associated with a small but definite risk of paradoxical embolism in patients with a patent foramen ovale (PFO). While neurologic complications are unfrequent the incidence of clinically silent brain infarction is unknown. We will assess the rate of clinically apparent and silent cerebral embolism in patients with a pulmonary embolism (PE) in relation to the presence or not of a PFO.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-10
• Study First Submitted: 2009-01-27
• Study First Submitted QC: 2009-01-27
• Study First Posted: 2009-01-28
• Primary Completion: 2009-04
• Study Completion: 2009-05
• Status Verified: 2011-05
• Last Update Submitted: 2011-05-19
• Last Update Posted: 2011-05-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Pulmonary embolism, informed consent signed, no-contraindication to MRI

Exclusion Criteria

• contra-indication to MRI, informed consent not obtained

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of cerebral infarcts as detected by Diffusion-weighted MRI	during hospitalization

Trial Locations

Locations (1)

USIC CHU de Caen; 🇫🇷 Caen, France