Effect of hemoperfusion with hexadecyl-immobilized cellulose beads on myocardial fatty acid imaging in hemodialysis patients: a case series study
Not Applicable
- Conditions
- Chronic kidney disease
- Registration Number
- JPRN-UMIN000033778
- Lead Sponsor
- Division of Clinical engineering, Toujinkai Hospital
- Brief Summary
The HICBs group showed a lower mean B2-MG than that of the non-HICBs group, while other clinical baseline patient characteristics did not differ between the HICBs and the non-HICBs groups. In the HICB group, the 2nd BMIPP SS was significantly decreased compared to that for the 1st BMIPP SS. A decrease in the BMIPP SS was observed in 9 (75%) patients with 1st BMIPP SS >= 6, and no change was observed in 3 patients with BMIPP SS <= 2. In the non-HICBs group, the 2nd BMIPP SS was significantly increased compared to that for the 1st BMIPP SS.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who received percutaneous coronary intervention or coronary artery bypass grafting during the observation period.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodialysis patients who had been treated with HICB columns for more than 4 years are assigned to the HICBs group, while the other patients were assigned to the non-HICBs group. All patients taked two BMIPP SPECTs at intervals of more than 3 years. The images were divided into 17 segments for semiquantitative analysis according to the standard myocardial segmentation for tomographic heart imaging established by the American Heart Association. The amount of radioactivity taken up by each segment was visually graded and assigned an uptake score of either 0 (normal), 1 (mildly reduced), 2 (moderately reduced), 3 (severely reduced), or 4 (none). The BMIPP SPECT scores for 17 myocardial segments were designated as the BMIPP summed score (SS). We compared first and second BMIPP SPECT SS in HICBs group and non-HICBs group.
- Secondary Outcome Measures
Name Time Method