International Surgical Trial in IntraCerebral Haemorrhage

Completed

• Conditions: euroscience, psychiatry; Nervous System Diseases; Intracerebral haemorrhage

• Registration Number: ISRCTN19976990
• Lead Sponsor: Medical Research Council (MRC) (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2000-10-23
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

1. Spontaneous, supratentorial intracerebral haemorrhage within 72 h and uncertainty about surgery
2. Minimum clot diameter of 2 cm on initial Computed Tomography (CT)
3. Glasgow Coma Score of 5 or above

Exclusion Criteria

1. Haemorrhage due to aneurysm or arteriovenous malformation
2. Cerebellar or brainstem haemorrhages or brainstem extensions of a supratentorial haemorrhage
3. ICH secondary to a tumour or trauma
4. Where surgery cannot be performed within 24 h of randomisation
5. Evidence of severe pre-existing physical or mental disability or of severe co-morbidity which might interfere with the assessment of outcome

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glasgow Outcome Scale (favourable = GR/MD: unfavourable = SD/V/D)/ Rankin & Barthel Scale/Mortality

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration