NCT00213993已完成2 期
Topical Antiperspirant for Prevention of Palmar-Plantar Erythrodysesthesia (Hand-Foot Syndrome) Associated With Capecitabine
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- reduction in palm and/or sole pain
研究概览
简要总结
The objectives of this study are to evaluate the effectiveness of an antiperspirant in preventing or attenuating the severity of palmer-plantar erythrodysesthesia associated with the Food and Drug Administration (FDA)-approved doses of capecitabine. The hypothesis is that cytotoxic compounds in sweat will be prevented from being deposited in the skin and causing chronic toxicity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Has not previously received a regimen that includes 5-fluorouracil
- •> 18 years old
- •No known allergy or intolerance to Ban Unscented Roll-On Antiperspirant
排除标准
- •< 18 years of age
研究组 & 干预措施
A
Experimental
antiperspirant topically to one foot once daily
干预措施: antiperspirant (Drug)
结局指标
主要结局
reduction in palm and/or sole pain
时间窗: after each of first four cycles of chemotherapy
次要结局
- evaluation of utility of digital photography in the following palmar-plantar erythrodysesthesia (PPES)(after each of first four cycles of chemotherapy)
研究者
研究点 (1)
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