Iterative Model-Based Reconstruction on Cervical Spine CT: <br>How low can you go? <br>

Recruiting

Conditions: cervical spine injury
fracture
10005942
10017322

Registration Number: NL-OMON46012

Lead Sponsor: Isala Klinieken

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 120

Inclusion Criteria

- Subjects >= 50 years old
- NEXUS-criteria positive
- Written informed consent.

Exclusion Criteria

- Hemodynamically unstable (hypotension < 90 mmHg)
- (Glasgow Coma Scale) EMV score < 15
- Previous participation in the study
- Pregnancy
- Intoxication (e.g. Alcohol, Drugs)
- Concomitant participation in a study in which the patient is exposed to X-rays
- History of psychiatric disorder which causes the patient to be incompetent to make a thought-out decision.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the current standard CT-scan and an additional<br /><br>low-dose CT-scan with 40%, 60% or 80% lowered radiation dose. The main endpoint<br /><br>is the subjective image quality at different radiation levels for iterative<br /><br>reconstruction and model-based iterative reconstruction. The subjective image<br /><br>quality, scored by two radiologists, will be leading in the acceptance of<br /><br>low-dose CT images. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary outcome measure is objective image quality at different radiation<br /><br>levels for iterative reconstruction and model-based iterative reconstruction.<br /><br>Hounsfield Units, noise, contrast-to-noise and signal-to-noise-ratios will be<br /><br>used to determine objective image quality.</p><br>