Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness

Not Applicable

Completed

• Conditions: Fluid Challenge; Shock; Hypotension; Fluid Responsiveness

• Registration Number: NCT01941472
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting. Investigators hypothesize that transcutaneous pO2,transcutaneous pCO2 and Central Venous SO2 variations provide feasible estimation on fluid responsiveness in critical ill patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-08-31
• Study Start: 2013-09
• Study First Submitted QC: 2013-09-09
• Study First Posted: 2013-09-13
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Results First Submitted: 2016-10-29
• Results First Submitted QC: 2017-01-12
• Status Verified: 2017-03
• Results First Posted: 2017-03-03
• Last Update Submitted: 2017-03-03
• Last Update Posted: 2017-04-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 18 years and older ICU patients;
• Septic shock;
• Monitored with PICCO or Swan-Ganz catheter;
• The decision of fluid challenge made by the treating physician;

Exclusion Criteria

• Evidence of fluid overload;
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Fluid Responsiveness	Immediately after fluid challenge, average 5 minutes	Increase in cardiac index ≥ 10% after fluid challenge

Trial Locations

Locations (1)

MICU of Peking Union Medical College Hospital; 🇨🇳 Peking, Beijing, China