NCT01941472CompletedNot Applicable
Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness
Peking Union Medical College Hospital1 site in 1 country40 target enrollmentStarted: September 2013Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Fluid Responsiveness
Study Overview
Brief Summary
Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting. Investigators hypothesize that transcutaneous pO2,transcutaneous pCO2 and Central Venous SO2 variations provide feasible estimation on fluid responsiveness in critical ill patients.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Screening
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •18 years and older ICU patients;
- •Septic shock;
- •Monitored with PICCO or Swan-Ganz catheter;
- •The decision of fluid challenge made by the treating physician;
Exclusion Criteria
- •Evidence of fluid overload;
- •Pregnancy
Outcomes
Primary Outcomes
Fluid Responsiveness
Time Frame: Immediately after fluid challenge, average 5 minutes
Increase in cardiac index ≥ 10% after fluid challenge
Secondary Outcomes
No secondary outcomes reported
Investigators
Bin Du
Director of Medical ICU
Peking Union Medical College Hospital
Study Sites (1)
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