Comparison of the effects of Pegagen and G-csf in the treatment of cytopenia induced by breast cancer chemotherapy
Not Applicable
- Conditions
- Breast cancer.Malignant neoplasm of breast
- Registration Number
- IRCT2017020732444N1
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
age >18 years old; absolute neutrophil count =1.5 × 109/l; platelet count =100 × 109/l; serum creatinine <1.5 × upper limit of normal.
Exclusion criteria: hypersinsitivity reaction; unwillingness of patients to continue; change of chemotherapy regimen.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eutrophil count. Timepoint: before chemothrapy and 1 weeks and 2 weeks later. Method of measurement: laboratory CBC.;Hb level. Timepoint: before chemothrapy and 1 weeks and 2 weeks later. Method of measurement: laboratory CBC.;Platelet count. Timepoint: before chemothrapy and 1 weeks and 2 weeks later. Method of measurement: laboratory CBC.;Drug reaction. Timepoint: before chemothrapy and 1 weeks and 2 weeks later. Method of measurement: questionnaire.;Wbc count. Timepoint: before chemothrapy and 1 weeks and 2 weeks later. Method of measurement: laboratory CBC.
- Secondary Outcome Measures
Name Time Method Fever. Timepoint: before chemotherapy and 1 week and 2 weeks later. Method of measurement: questionnaire.;Abdominal pain. Timepoint: before chemotherapy and 1 week and 2 weeks later. Method of measurement: questionnaire.;Dyspnea. Timepoint: before chemotherapy and 1 week and 2 weeks later. Method of measurement: questionnaire.;Bone pain. Timepoint: before chemotherapy and 1 week and 2 weeks later. Method of measurement: questionnaire.;Hypersensitivity reactions. Timepoint: before chemotherapy and 1 week and 2 weeks later. Method of measurement: questionnaire.;Postpone chemotherapy. Timepoint: 2 weeks after chemotherapy. Method of measurement: questionnaire.