SOLIDARITY TRIAL PLUS: An international randomized trial of additional treatments for COVID-19 in hospitalized patients who are all receiving the local standard of care

Not Applicable

Completed

• Conditions: Additional treatments for COVID-19 in hospitalized patients who are all receiving the local standard of care; Infections and Infestations; COVID-19 (SARS-CoV-2 infection)

• Registration Number: ISRCTN18066414
• Lead Sponsor: World Health Organization

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-29
• Study Completion: 2023-11-14
• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

The only patients invited will be those admitted to a collaborating hospital; no wider recruitment is expected.
1. Adults (age =18 years, which allows consent)
2. Recently hospitalized (or already in hospital) with laboratory-confirmed COVID
3. Not expected to be transferred within 72 hours
4. With, in the view of their doctors, no contra-indication to any potentially relevant study drug

Exclusion Criteria

Does not meet inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In-hospital mortality in all patients measured using patient records up to the end of hospital stay

Secondary Outcome Measures

Name	Time	Method
Measured using patient records:<br>1. Initial respiratory support (yes/no)<br>2. Initiation of ventilation in lower-risk patients (yes/no)<br>3. Duration of hospital stay (days)