Does the Injection Rate of Local Anesthetic Affect the Onset of Sensory Block and Incidence of Hypotension in Caesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 67
- 试验地点
- 2
- 主要终点
- sensory block
研究概览
简要总结
This randomized double-blind study aimed to compare the effects of two different subaracnoid lokal anesthetic injection rate in cesarean section. Totally 67 patients were included. The groups were compared in terms of maximum sensory and motor block level, time to reach T6 level, hemodynamic changes and nausea- vomiting saved.
详细描述
A total of 67 patients 18-40 years undergoing cesarean, who were graded as American Society of Anesthesiologists physical status were randomly allocated into two groups, 120-sn injection time (n=34, Group F), 15-sn injection time (n=33, Group S). When the level of the sensory block achieve the T6 level the surgery was let to begin. The groups were compared in terms of hemodynamic values, use of efedrin, the time to achieve sensory block to the T6 level, maximum sensory block level and motor block level.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Anesthesiologists risk score (ASA) I-II risk status
- •Singleton pregnancy aged
- •Between 18-40 years
排除标准
- •Pregnant women with contraindications for spinal anesthesia;
- •Placental anomaly;
- •Hypertension
- •Cardiac disease
- •Vascular disease
- •Hepatic disease
- •Renal disease
- •Hemodynamic instability
- •Spinal deformity;
- •Severe mental retardation
- •Weight < 50 kg or >110 kg; height < 140 cm or > 180 cm
- •Metabolic and Acid-base balance disorders
- •Emergency patients
结局指标
主要结局
sensory block
时间窗: 2 minutes interval
The time to reach the sufficient sensory block and maximum level of sensory block was significantly shorter in Group S
Hypotension
时间窗: 2 minutes interval
The time to onset of hypotension was significantly shorter in Group F
次要结局
未报告次要终点
研究者
Ersagun Tugcugil
Ass. Prof.
Karadeniz Technical University