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Dairy vs Plant-based Beverages for Improving Bone Health During Exercise

Not Applicable
Not yet recruiting
Conditions
Osteoporosis
Registration Number
NCT06946316
Lead Sponsor
University of Saskatchewan
Brief Summary

This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.

Detailed Description

The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
150
Inclusion Criteria
  • Women need to be postmenopausal (no age limit)
  • Men need to be 50y or older
Exclusion Criteria
  • Taking medications that might affect bone
  • Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
  • Planning 6 weeks of travel during the 12 month intervention period
  • Planning major surgery during the 12 month intervention period
  • Already strength training greater than 2 days per week for 30 minutes or longer per session
  • Allergies to ingredients in the beverages

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change in section modulus at the hip (cm to the power of 3)12 months

Section modulus measured by dual energy X-ray absorptiometry

Secondary Outcome Measures
NameTimeMethod
Change in hip bone mineral density (g/cm-squared)12 months

Hip bone mineral density measured by dual energy X-ray absorptiometry

Change in cross-sectional area at the hip (cm-squared)12 months

Cross-sectional area measured by dual energy X-ray absorptiometry

Change in cortical thickness at the hip (cm)12 months

Cortical thickness measured by dual energy X-ray absorptiometry

Change in buckling ratio at the hip (no units)12 months

Buckling ratio measured by dual energy X-ray absorptiometry

Change in bench press strength (kg)6 and 12 months

Bench press strength determine from 1-repetition maximum

Change in knee extension strength (kg)6 and 12 months

Knee extension strength determined from 1-repetition maxium

Change in lean tissue mass (kg)12 months

Lean tissue mass measured by dual energy X-ray absorptiometry

Change in fat mass (kg)12 months

Fat mass measured by dual energy X-ray absorptiometry

change in 30 second sit to stand (number of repetitions)6 and 12 months

Maximal number of times sitting and standing in 30 seconds

Change in walking speed (m/s)6 and 12 months

walking speed measured over 10 m

Change in timed up and go performance (s)6 and 12 months

Time for standing from a chair, walking 6 meters and sitting back down

Change in lumbar spine bone mineral density (g/cm-squared)12 months

Lumbar spine bone mineral density measured by dual energy X-ray absorptiometry

Trial Locations

Locations (1)

College of Kinesiology University of Saskatchewan

🇨🇦

Saskatoon, Saskatchewan, Canada

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