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临床试验/CTRI/2025/03/082451
CTRI/2025/03/082451尚未招募不适用

To Compare The Efficacy of Vidanga Churna Pradhamana Nasya With Vidanga Taila Nasya In Kaphaja Shirashula-Chronic Rhino Sinusitis-An Open Label Double Arm Randomised Clinical Study

未提供1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年6月4日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
40
试验地点
1
主要终点
•To assess the effect of Vidanga Churna Pradhamana nasya in relieving the complaints of Kaphaja Shira Shula (Chronic Rhino Sinusitis) on the basis of subjective and objective parameters.

研究概览

简要总结

Sinusitis is a widespread health issueaffecting millions of people worldwide. It may be acute or chronic it canresult from various causes such as infections, allergies, or structural issues,causing symptoms such as facial pain, headaches, nasal congestion, anddifficulty in breathing; these symptoms significantly impact a person’s dailylife and can impose a significant economic burden on individuals, by findingtreatments which are cost effective, healthcare costs related to sinusitis canbe reduced, that include doctor visits, medications, and surgicalinterventions.  Understanding anddeveloping effective treatments are necessary to alleviate these symptoms andimprove the quality of life. Chronic rhino sinusitis is the inflammation of thenasal cavity and Para nasal sinuses in which the symptoms lasts more than 12weeks Untreated sinusitis causes complications, such as the spread of infectionto the nearby structures or the development of chronic inflammation. Studyingtreatment protocols help prevent these complications and help improve patientoutcome which is a crucial aspect of healthcare research.

Chronic rhino sinusitis affects 1 in 8people in India and about 5 to 15 percent of urban population.

 Acharya Sushruta has mentioned 11types of Shiroroga in uttara tantraand KaphajaShiroroga is one of them in this condition we find symptoms like kaphaupadigdha shira  kapha upadigdhagala, guruta, shuna akshi kuta and vadana, Acharyavaghbattaalso explains kaphajashirashula as one among the ten shirorogas presenting with mandaruk, shiro guruta, which resemble the symptoms of chronic rhinosinusitis.

 The available treatments for chronicrhino sinusitis include nasal steroid drops/ sprays, antibiotics, analgesics,anti-histamines, decongestants and surgical interventions which providetemporary symptomatic relief with a high chance of reoccurrenceandare economically draining.

In Ayurveda the line oftreatment for kaphaja shirashula includes shirovirechana, teekshnavamana, pradhamana , gandusha dharana of which nasya isone of the prime treatment modality as it is rightly pointed nasa hishiraso dwaram” nose is the gateway of the shiras

Among these different set oftreatments, a research study on VidangaTaila has been proved to be effective in treating Chronic Sinusitis.

According to Acharya Charaka Pradhamanawith teekshna dravyas *(Shirovirechana Dravyas)*ismentioned as one of the important treatment modality for Kaphaja Shirashula, Vidangais one among the shirovirechana dravyasit is ruksha and teekshna in guna it is kaphavatahara,krimigna and vishagna theseproperties help in doing the kaphavilayana thus efforts are put forth toCompare The Efficacy of Vidanga TailaNasya with Vidanga Churna Pradhamana**Nasya In Kaphaja Shirashula.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
20.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • •1.Patients presenting with lakshanas kaphaja shirashula (chronic rhinosinusitis) 2.Age 20-50 years 3.Patients of either sex 4.Patients fit for Nasya Karma 5.Chronicity less than 1 year.

排除标准

  • •1.Patients suffering with other types of Shiroroga 2.Patients with complications of chronic sinusitis such as orbital cellulitis,osteomyelitis 3.Patients with nasal polyps 4.Cases of inverted papilloma 5.Malignancy 6.Congenital anomalies of nose and sinus 7.Patients with gross Deviated Nasal Septum 8.Patients unfit for nasya karma.

结局指标

主要结局

•To assess the effect of Vidanga Churna Pradhamana nasya in relieving the complaints of Kaphaja Shira Shula (Chronic Rhino Sinusitis) on the basis of subjective and objective parameters.

时间窗: 7th day 15th day

次要结局

  • •Decrease in score in SNOT 22 from base score(7th day 15 th day)

研究者

发起方
未提供

研究点 (1)

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