An open labelled clinical trial to evaluate the combined effect of Apamarga Kshara Pratisarana with Vachadi Kwatha Kavala and Kaishora Guggulu in Tundikeri with special reference to chronic tonsillitis in children.”
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- To evaluate the combined effect of Apamarga Kshara Pratisarana with Vachadi Kwatha Kavala &
研究概览
简要总结
The treatment principles of Ayurveda aim at eliminating the impurities. Kaumarabhritya, one among
the Ashtanga’s of Ayurveda exclusively deals with the child care both preventive and curative. As the
definition of Bala signifies, vulnerability of children to acquire disease is more when compared to an
adult.
A disease Tundikeri, explained by Ancient Ayurvedic classics under Mukhagata rogas lI7 and
Talugata Rogas |3455,71 appearing as a SthanikaShotha (local swelling) is one such disease in children,
caused due to an excess consumption of Guru, Snigdha, Amla and Abhishyandi Ahara’s leading to
Kapha, Pitta and Rakta Dusti. The Lakshanas of the disease Tundikeri mentioned in Ayurveda classics
are characterized by Sthoolashotha (hard swelling), Toda (pricking type of pain), Daha (burning
sensation), Prapaki (tend to undergo suppuration) and Avrodha (creates obstruction in throat for
respiration and deglutition) (SI. Acharya mentioned line of management of Tundikeri in Ayurveda similar
to that of Galashundika which include Shastra karma, Pratisarana, Kavala, Dhuma and use of Yushal°
According to Acharyas, common line of management of Kantharogas is also applicable to Tundikeri.
Thisinclude Kayshirovirechana, Vamana, Katu Tikta Kavala Graha, Raktavisravana, Kapharaktahara
Karma, Raktamokshana, Tikshna nasya, Pratisarana or Kavala, Lepana(101
Immunological protection of a newborn will be done by maternal antibodies and developed naturally
later in life through infection or artificially by immunization. Their inherent immunity diminishes within
months After birth. Whenever there is an infection in the oral cavity or respiratory tract, the tonsils act as
sentinels to guard against foreign intruders like viruses, bacteria and other antigens coming into contact
through inhalation and ingestion (’"I
Chronic tonsillitis in children may be described as a sore throat for 3 months or more, associated
with inflammation of the tonsils, presenting with features like chronic sore throat, halitosis, a foreign
body sensation in the throat, or a history of expelling smelly foul-tasting cheesy lumps 11Z. It profoundly
affects the child’s quality of life, having an impact on their ability to work, sleep, and enjoy daily
activities, leading to an inevitable school absence.If medicinal treatments are unsuccessful, then the final
option is to undergo a tonsillectomy surgery in those patients who have had sequelae, such as
peritonsillar abscess, lemierre syndrome, minimum frequency of sore throat episodes 7 or more in the
preceding year, cervical lymphadenopathy, tonsillar exudates, sleep apnea due to tonsillar hypertrophy
[13)
When considering tonsillectomy surgery, the surgery is associated with risks, can potentially pose
serious risks to a child’s health. The persistent inflammation and infection of the tonsils can lead to
complications that could become life threatening if not addressed. acute respiratory infections are a major
cause of children in India. Outpatient attendance attributed to acute respiratory infections is as high as
2040% of all outpatients and 12-35% of in patients.
Hence, an effective line of management intending to scrape out the inflamed cells with the retention
of surrounding normal tissues in chronic tonsillitis is a need of hour, so that the faster healing with less
or no recurrence of incidences will be achieved by the following treatment. Treatment with oral medication like Kaishora Guggulu along with various local drug application
methods like Apamarga Kshara Pratisarana, and Gargling with Vachadi Kwatha Kavala.
As Apamarga Kshara, known for its ushna (hot) and Tikshna (sharp) properties, plays a crucial role
in managing Tundikeri. It readily burns inflamed cells, aids wound cleansing, and accelerates healing by
promoting both vrana shodhana (cleansing of wounds) and Ropana (healing) (14)
Additionally, Vachadi Kwatha Kavala is effective in treating GalashundikaRoga which is similar to
Tundikeri within the context of Taluroga Chikitsal’5). Furthermore, Kaishora Guggulu is beneficial for
addressing conditions such as Mandagni, Kasa, Shwasa, and Shothall
Therefore, the present study is planned to evaluate the combined effect of Apamarga Kshara
Pratisarana with VachadiKwatha Kavala and Kaishora Guggulu in Tundikeri w.s.r to chronic Tonsillitis
in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 5.00 Year(s) 至 12.00 Year(s)(—)
- 性别
- All
入选标准
- •Children aged between 5 to 12 years.
- •Children fulfilling the diagnostic criteria with or without 1 or more symptoms of Pricking pain(Toda),Burning sensation (Daha), Suppuration (Paka), Recurrent or persistent sore throat, Irritation of throat, Halitosis, Sensation of obstruction of food in throat.
排除标准
- •Children with syndromic or other systemic illness with or without medication.
- •Children with acute exacerbation of chronic tonsillitis, sinusitis, ear infection, fever etc.
- •Children presenting with complications of tonsillitis.
结局指标
主要结局
To evaluate the combined effect of Apamarga Kshara Pratisarana with Vachadi Kwatha Kavala &
时间窗: To evaluate the combined effect of Apamarga Kshara Pratisarana with Vachadi Kwatha Kavala and | Kaishora Guggulu in symptomatic reduction of chronic tonsillitis in children | Duration 21 days | Follow up after 7 days | Total - 28 days
Kaishora Guggulu in symptomatic reduction of chronic tonsillitis in children.
时间窗: To evaluate the combined effect of Apamarga Kshara Pratisarana with Vachadi Kwatha Kavala and | Kaishora Guggulu in symptomatic reduction of chronic tonsillitis in children | Duration 21 days | Follow up after 7 days | Total - 28 days
次要结局
- Children with enlarged tonsils/sthoola shopha(28 days)
研究者
Dr amarnath dunage
Sdm college of ayurveda hospital and research centre kuthpady, udupi.
