Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status
Overview
- Phase
- Not Applicable
- Intervention
- Paraclinical examination
- Conditions
- Covid19
- Sponsor
- Centre Hospitalier Universitaire Dijon
- Enrollment
- 543
- Locations
- 1
- Primary Endpoint
- Respiratory sequelae 6 months after resuscitation.
- Status
- Completed
- Last Updated
- 2 months ago
Overview
Brief Summary
In this study, the investigators are attempting to evaluate the influence of socio-economic factors on the functional recovery (physical and psychological) of patients who developed ARDS after a COVID-19 infection, with the aim of offering personalized medical and social follow-up and support measures in order to avoid medium- and long-term complications, which can result in handicaps, reduced quality of life, and a higher risk of death.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Inpatient in ICU for PCR-proven SARS-VOC-2 infection regardless of specimen type
- •Patient who received a chest CT scan in the initial phase of management (either just before or during hospitalization in the intensive care unit)
- •Patient who has received invasive or non-invasive ventilatory support, or humidified and heated high-flow oxygen (HFO).
- •ARDS meeting the criteria of the 2012 Berlin definition. For patients who have received only HFO, a flow rate at least equal to 50L/minute with a FiO2 strictly greater than 50% with a PaO2/FiO2 ratio less than or equal to 200 will be required for inclusion.
- •Patient who gave oral consent after being informed about the conduct of this study.
Exclusion Criteria
- •Patient with limited autonomy prior to hospitalization in limited intensive care unit: walking distance of less than 50 meters, WHO classification status 3 and
- •Patient with a history of chronic respiratory failure as defined by the use of long-term oxygen therapy or non-invasive home ventilation, excluding patients with SAS and/or hypoventilation obesity syndrome.
- •Patient with a history of central or peripheral neurological conditions limiting the patient's motor autonomy and the performance on gait tests or Pulmonary function Tests
- •Patient refusing to participate
- •Patient \< 18 years of age
- •Patient not affiliated or not benefiting from national health insurance
- •Patient under guardianship, curatorship or protected adult
- •Patient unable to understand and consent to the research protocol
- •SECONDARY EXCLUSION CRITERIA
- •Patient not showing up for visit at M6
Arms & Interventions
Patient
Patient hospitalized in ICU for PCR-proven SARS-COV-2 infection
Intervention: Paraclinical examination
Patient
Patient hospitalized in ICU for PCR-proven SARS-COV-2 infection
Intervention: Clinical Examination
Patient
Patient hospitalized in ICU for PCR-proven SARS-COV-2 infection
Intervention: Semi-directive interview
Patient
Patient hospitalized in ICU for PCR-proven SARS-COV-2 infection
Intervention: quality of life questionnaires
Outcomes
Primary Outcomes
Respiratory sequelae 6 months after resuscitation.
Time Frame: Through study completion, an average of 6 months
Defined by the presence of at least one of the following : * An alteration of the alveolar-capillary diffusion of CO \<80% of the predicted normal values * And/or a forced vital capacity \<80% of predicted normal values * and/or O2 desaturation in the 6-minute walk test * And/or pulmonary parenchymatous disease with fibrosis in tomodensitometry.