ACTRN12611000766910
Recruiting
Phase 2
Randomised blinded control pilot trial investigating the effect of N-acetylcysteine in the treatment of acute decompensated heart failure
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Alfred Health
- Enrollment
- 70
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Hospital admission with acute decompensated HF including congestion (or) hypotension (or) worsening renal function (or) other end organ dysfunction.
- •\-NYHA Class III or IV
- •\-LVEF \< 40%
Exclusion Criteria
- •Age \< 18, and \>75
- •\-LVAD or ECMO in situ or likely requirement for LVAD/ECMO within 24 hrs
- •\-endotracheal intubation/ventilation
- •\-cardiac or other solid organ transplantation
- •\-STEMI at presentation
- •\-Allergy to n\-acetylcysteine
- •\- pregnancy
Outcomes
Primary Outcomes
Not specified
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