Value of CA125 and Yolk Sac Morphology in Prediction of Pregnancy Outcome in Threatened Miscarriage

Completed

• Conditions: Threatened Miscarriage in First Trimester

• Registration Number: NCT03320213
• Lead Sponsor: Ain Shams University

Brief Summary

evaluation of serum CA125 level and yolk sac morphology in women with threatened miscarriage is very important to predict pregnancy outcome

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design

Study Timeline

• Study Start: 2016-10-01
• Primary Completion: 2017-07-30
• Study Completion: 2017-07-30
• Status Verified: 2017-10
• Study First Submitted: 2017-10-08
• Study First Submitted QC: 2017-10-20
• Last Update Submitted: 2017-10-20
• Study First Posted: 2017-10-25
• Last Update Posted: 2017-10-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 192

Inclusion Criteria

• pregnant women between 20-40 years. Pregnancy between 6-10 weeks. single intrauterine spontaneous pregnancy. vaginal bleeding or bloody vaginal discharge with or without pelvic pain for patients with threatened miscarriage.

Read More

Exclusion Criteria

• medical disorders with pregnancy. History of recurrent miscarriage. Any maternal disease that would cause an increase in CA125 level. Local gynecological disorders e.g. fibroid. Presence of any uterine malformation. History of congenital abnormalities in previous pregnancy Presence of multiple pregnancy. Presence of anembryonic sac. Absent fetal heart pulsation.

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of serum CA125	6 - 10 weeks	Measuring serum level of CA125 by ELIZA kits.
Evaluation of yolk sac morphology	6 - 10 weeks	Evaluating yolk sac size and shape by transvaginal ultrasound

Secondary Outcome Measures

Name	Time	Method
follow up of participants	up to 20 weeks.	measuring crown rump length by transvaginal ultrasound.