Identifying Rheumatoid Arthritis in the preclinical phase - Extension of the observational Leiden Clinically Suspect Arthralgia (CSA) cohort in the Medical Delta to enable sufficiently powered studies with the ultimate aim to arrive at proper accuracy to identify imminent Rheumatoid Arthritis.
Recruiting
- Conditions
- 1000381610023213rheumatoid arthritis
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
- Arthralgia on hand, wrist or feet joints that is according to the rheumatologist clinical suspect to become RA (e.g. because of an inflammatory type or the presence of morning stiffness)
- Recent onset of complaints (< 1 year)
- Age > 18 years
- Written informed consent
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study as this precludes the presence of CSA:
- Presence of, or history of, clinically apparent arthritis
- Previous or current treatment with DMARDs or corticosteroids
- If another condition or explanation for the pain is more likely (other than imminent RA), a patient does not have CSA
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Clinical arthritis detected at physical examination by the rheumatologist,<br /><br>persisting arthritis (present at two subsequent visits) or initiation of<br /><br>treatment with Disease Modifying Anti-Rheumatic Drugs (DMARDs).</p><br>
- Secondary Outcome Measures
Name Time Method <p>na</p><br>