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临床试验/NCT06673381
NCT06673381招募中不适用

Prediction of Acute Coronary Syndrome In-hospital Major Adverse Cardiovascular Events by High Sensitivity C- Reactive Protein to Albumin Ratio

Sohag University1 个研究点 分布在 1 个国家目标入组 240 人开始时间: 2024年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
240
试验地点
1
主要终点
assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in acute coronary syndrom patients

研究概览

简要总结

assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients

详细描述

Observational study conducted at coronary care unit(CCU) in sohag university hospital It included patients with ACS diagnosed according to AHA/ACCF guidelines (according to symptoms, ECG findings and serum troponin levels), who had admitted to the CCU.

Venous blood samples were instantly collected on admission to the hospital. hs-CRP , serum albumin level were measured.

hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR) In-hospital MACE was regarded as the end point of our study. It was defined as acute heart failure, cardiogenic shock, reinfarction, all-cause death, serious arrhythmia and cardiac death

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All patients aged 18 Year or older presented by ACS not candidet for primary percutaneus coronary intervention ( PCI ) .

排除标准

  • • Patients aged < 18 years old
  • Patients who have eGFR <60 ml/kg /m2
  • Patients who have malignancies
  • Patients who have chronic heart failure (NYHA class >II)
  • Pateints who have chronic liver disease
  • Patients who have nephrotic syndrome
  • Patients who have acute cerebrovascular stroke
  • Pregnant women
  • Patients who have recent infection

结局指标

主要结局

assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in acute coronary syndrom patients

时间窗: at time of admission in hospital

Venous blood samples were collected on admission to the hospital. hs-CRP , serum albumin level were measured. hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR)

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amira Elbasuony Morsy

Resident at internal medicine department

Sohag University

研究点 (1)

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